Journal of Natural Science Research and Review (JNSRR)

Quorum Sensing: Biochemical Mechanisms and Implications

David, Bando Christopher, Tutuwa, Jummai Adamu, Polly, Jesse Shingu, Joshua, Uwhe Efi, Ngozi, Odii Josephine, Blessing, Smart Aigbogun, Patience, Angyu Jonathan

22 September 2026 · Vol. 2, Issue 9, pp. 294-306

DOI: 10.65150/EP-jnsrr/V2E9/2026-01

Abstract

Quorum sensing (QS) is a key component of microbial communication, which controls collective behaviours in response to cellular density. Microbial organisms are mainly able to coordinate a number of physiological functions, including sporulation, motility, biofilm formation, pathogenicity, antibiotic resistance, and the synthesis of secondary metabolites, by using this complex signalling system. QS depends on the synthesis, identification, and reaction to auto-inducers; which are signalling molecules. Extensive research on the molecular principles behind QS has shown highly organized systems involving a variety of chemical signals and receptor pathways in many bacterial ecosystems. The molecular support of quorum sensing, the differences across microbial species; gram positive and gram negative, molecular mechanism of signal interference which are quorum sensing inhibition and quorum quenching and the wider applications of QS in biotechnology, microbial ecology, agriculture, and medicine are all examined in this review work.

Keywords: Quorum sensing, Microbial, Biofilm, Receptor, Inducer

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David, Bando Christopher, Tutuwa, Jummai Adamu, Polly, Jesse Shingu, Joshua, Uwhe Efi, Ngozi, Odii Josephine, Blessing, Smart Aigbogun, Patience, & Angyu Jonathan (2026). Quorum Sensing: Biochemical Mechanisms and Implications. Journal of Natural Science Research and Review, 2(9), 294-306. https://doi.org/10.65150/EP-jnsrr/V2E9/2026-01

@article{David2026,
  title   = {Quorum Sensing: Biochemical Mechanisms and Implications},
  author  = {David and Bando Christopher and Tutuwa and Jummai Adamu and Polly and Jesse Shingu and Joshua and Uwhe Efi and Ngozi and Odii Josephine and Blessing and Smart Aigbogun and Patience and Angyu Jonathan},
  journal = {Journal of Natural Science Research and Review},
  year    = {2026},
  volume  = {2},
  number  = {9},
  pages   = {294-306},
  doi     = {10.65150/EP-jnsrr/V2E9/2026-01},
  url     = {https://doi.org/10.65150/EP-jnsrr/V2E9/2026-01}
}

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